New York Cardiovascular Symposium
December 11 − 13, 2015
New York Hilton Midtown
New York City

Course Director(s): Valentin Fuster, MD, PhD, MACC

Conflict of Interest (COI) Policy / Disclosures

ACCF committee members, faculty, staff and other individuals who are in a position to control the content of this activity are required to disclose all relevant financial relationships he/she and/or his/her spouse or domestic partner has, occurring within the past twelve months, with any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. All relevant potential conflicts of interest that are identified are thoroughly vetted through a process that includes course directors and appropriate peer review by education committee chairs/members, for fair balance, scientific objectivity and validity, patient care and safety recommendations. Refer to the links below for committee member disclosures and course faculty disclosures. Please note ACCF staff involved with this course have nothing to disclose.


AGENDA

Friday, December 11

Coronary Artery Disease -- Challenges in 2015
Session I: New Discoveries in Athero-thrombogenesis and Technologies
Dr. Bhatt, Presiding

7:30 a.m. Noninvasive Evaluation of Subclinical Atherosclerotic Disease Burden
A Powerful Prognostic Tool Implicating Heart, Brain and Aging
Dr. Fuster
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8:00 a.m. Invasive Evaluation of High Risk or Vulnerable Plaque
A Powerful Therapeutic Tool to Address Potential Pharmacological Agents
Dr. Narula
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8:25 a.m. The Role of the Various Monocyte Types in Athero-thrombotic Disease
Protective vs. Detrimental Effects and Therapeutic Implications
Dr. Nahrendorf
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8:50 a.m. Panel Discussion
Drs. Fuster, Nahrendorf and Narula
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Session II: Acute Coronary Syndromes (ACS)
Dr. Bonow, Presiding

9:40 a.m. ACS – Recent and Evolving Aspects
Definition and Diagnostics, Acquired and Genetic Factors, Ischemic and Reperfusion Injury

Dr. Kovacic
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10:05 a.m. ACS: Timing-related Strategies or a Most Critical Issue?
Timing to Reperfusion, Timing of Culprit vs. Multivessel Approach, Timing of DAPT

Dr. Granger
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10:30 a.m. ACS: Antiplatelet, Anticoagulant Therapy and Combinations
The Challenge of a High Benefit/Bleeding Ratio

Dr. Bhatt
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10:55 a.m. ACS: Non-antithrombotic Medical Options
Old Agents and New Lines on the Horizon

Dr. Boden
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11:25 a.m. Panel Discussion
Drs. Bhatt, Boden, Granger and Kovacic
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Session III: Chronic Coronary and Systemic Arterial Disease
Dr. Boden, Presiding

1:00 p.m. Complex Stable CAD: Evolving Management Strategies
Anatomy (SYNTAX), Ischemia (FAME), Microcirculation (BARI) and the Polypill
(FREEDOM)

Dr. Fuster
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1:25 p.m. Severe Left Ventricular Dysfunction: Evolving Revascularization Strategies
Presence or Absence of Ischemia and Viability Testing (STICH)

Dr. Bonow
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1:45 p.m. Carotid Disease: How the 2014-2015 Data Will Influence Management
The Symptomatic vs. the Asymptomatic Patient Challenges

Dr. White
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2:05 p.m. Coronary Artery Manifestations of Fibromuscular Dysplasia
An Infrequent Condition, but Easily Missed

Dr. Olin
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2:25 p.m. Panel Discussion
Drs. Bonow, Creager, Fuster and White
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Session IV: Trends and Challenges of Prevention
Dr. Williams, Presiding

3:15 p.m. Recent ACC/AHA Guidelines on Lipids, Already Getting Older
From Ezetimibe/Simvastatin (IMPROVE IT) to PCSK9 Inhibitors

Dr. Sabatine
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3:35 p.m. New U.S. (and ESH/ESC) Statements on Hypertension; Healthy Controversy?
From Population Salt Reduction to Personalized Treatment Targets?

Dr. Rosendorff
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3:55 p.m. The Link Between Obesity and Diabetes
The Rapid Evolution and Positive Results of Bariatric Surgery

Dr. McGuire
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4:15 p.m. Aspirin Therapy in Primary Cardiovascular Disease Prevention
Only for Those at High Cardiovascular Risk, the Dose Under Trials

Dr. De Caterina
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4:35 p.m. Targeting Programs of Promoting Cardiovascular Health Are Finally Providing Data of Benefit
Targeting Children (Ages 3 to 5), the Family and the Community

Dr. Fuster
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4:55 p.m. Panel Discussion
Drs. De Caterina, Fuster, McGuire, Rosendorff and Sabatine
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5:30 p.m. Adjournment  

Saturday, December 12

Cardio-pulmonary and Electrical Failure 2015
Session V: Systolic Heart Failure and Basis for Management
Dr. O'Connor, Presiding

7:00 a.m. MOGE(S) or Clinical-genetic Classification of Cardiomyopathy and a Follow-up Critique
The Term “Idiopathic” in the Process of Eradication

Dr. Narula
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7:20 a.m. The 2015 Diagnostic and Prognostic Imaging (MR, CT) of the Various Cardiomyopathies:
Myocarditis, Dilated, Infiltrative (Amyloid, Sarcoid), Hypertrophic, Noncompaction

Dr. H. Halperin
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7:40 a.m. Systolic Dysfunction: Clinical/Hemodynamic Guide for Management
New Medical and Interventional Therapeutic Challenges

Dr. Mancini
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8:00 a.m. Diastolic Dysfunction: Clinical/Hemodynamic/Comorbid Features
Should Prognosis/Management Be Focused on the Comorbidities?

Dr. O’Connor
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8:20 a.m. Destination LVADs: Advances 2014-2015
A Rapidly Evolving Alternative to Heart Transplantation

Dr. Pinney
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8:40 a.m. Percutaneous Mechanical Circulatory Support Devices
Hemodynamic Effects, Clinical Outcomes, Risks and Knowledge Gaps

Dr. Rihal
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9:00 a.m. 2015 State-of-the-Art Management of Pulmonary Hypertension
Based on an Understanding of the Various Etiologies

Dr. McLaughlin
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9:20 a.m. Panel Discussion
Drs. Halperin, Mancini, McLaughlin, Narula, Pinney, O’Connor and Rihal
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Session VI: Rhythm Disorders, Contemporary and Future Topics of Focus
Dr. Reddy, Presiding

10:20 a.m. Heart Failure Device Therapy: ICD and CRT
Systolic Dysfunction, Diastolic Dysfunction, Mitral Regurgitation

Dr. Ellenbogen
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10:40 a.m. Ventricular Tachycardia: Catheter Ablation
How? When?

Dr. Wilber
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11:00 a.m. Atrial Fibrillation 2015: The 14 Clinical Challenges
Quality of Life and Preventing Stroke

Dr. Fuster
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11:20 a.m. Atrial Fibrillation: Catheter Ablation with New Technologies
Improving Quality of Life and Outcomes in Various Disease States

Dr. Wilber
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11:40 a.m. A New Job for the EP Community: Plumbing Electrical Dysfunction and Thromboembolism
Wireless “Boxes” and Protecting “Umbrellas”

Dr. Reddy
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12:00 p.m. Panel Discussion
Drs. Ellenbogen, Fuster, Reddy and Wilber
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Valvular Heart Disease and Aorta — Challenges in 2015
Session VII: Management of Aortic Valve Disease, IHSS and Aorta
Dr. Carabello, Presiding

1:30 p.m. Aortic Valvular Stenosis, Asymptomatic, Severe, Age 60 Years
From Medical Therapy, to Surgical AVR, to Transcatheter AVR/Valvuloplasty


The Clinician's View – Dr. Bonow
The Surgeon’s View – Dr. Bavaria
The Interventionalist's View – Dr. Sharma

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1:50 p.m. Aortic Valvular Stenosis, Symptomatic Severe, Low Flow/ Low Gradient, Age 60 Years
From Medical Therapy to Surgical AVR to Transcatheter AVR/Valvuloplasty


The Clinician’s View – Dr. Bonow
The Surgeon’s View – Dr. Bavaria
The Interventionalist’s View – Dr. Sharma

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2:10 p.m. 2015 Prevalence, Genetics and Approach to the Management of HCM
Evidence and Uncertainties

Dr. McGuire
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2:35 p.m. Aortic Valvular Incompetence, Asymptomatic, EF 45%, Age 60 Years
From Medical Therapy to Surgical AVR to Transcatheter AVR (?)


The Clinician’s View – Dr. Bonow
The Surgeon’s View – Dr. Bavaria
The Interventionalist’s View – Dr. Sharma

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2:55 p.m. Aortic Valvular Incompetence, Symptomatic, Infective Endocarditis, Age 25 Years
From Medical Therapy to Surgical AVR to Transcatheter AVR (?)


The Clinician’s View – Dr. Bonow
The Surgeon’s View – Dr. Bavaria
The Interventionalist’s View – Dr. Sharma

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3:15 p.m. The Dilated Thoracic and Abdominal Aorta and Complicating Dissection
Evolving Understanding of the Basic Biology and Management

Dr. Fuster
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3:40 p.m. Panel Discussion
Drs. Bavaria, Bonow, Fuster, Maron and Sharma
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Session VIII: Management of Mitral Regurgitation
Dr. Bavaria, Presiding

4:20 p.m. Secondary Mitral Valve Regurgitation in Heart Failure, Age 60 Years
From Medical Therapy to Surgical Repair to Transcatheter Intervention


The Clinician’s View – Dr. Carabello
The Surgeon’s View – Dr. Anyanwu
The Interventionalist’s View – Dr. Sharma

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4:40 p.m. Primary Mitral Valve Regurgitation without/with Heart Failure, Age 60 Years

The Clinician’s View – Dr. Carabello
The Surgeon’s View – Dr. Anyanwu
The Interventionalist’s View – Dr. Feldman

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5:00 p.m. Panel Discussion
Drs. Anyanwu, Carabello and Feldman
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5:30 p.m. Adjournment  

Sunday, December 13

YEAR IN REVIEW: 10 HIGHLIGHTS OF PROGRESS IN 2015
Dr. Fuster, Presiding
Session IX: Novelties on Genetics, Cell Regeneration and Molecular Signaling

7:30 a.m. HENRY RUSSEK LECTURE 2015
The microRNAs: Evolving Critical Players in the Field of Medicine
Genetic and Molecular Bases for a Better Understanding of Cardiovascular Physiology and Pathology

Dr. Mayr
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7:55 a.m. Induced Pluripotent Stem Cells: Predicting a Powerful Future
Dr. Wu
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8:15 a.m. Follow-up of the CUPID Gene Therapy Studies
A Roadmap for Enhancement of Myocardial Metabolism and Viability

Dr. Hajjar
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Section X: Novelties on Diagnostic Strategies

8:35 a.m. Peripheral Vascular Disease: Watch the Heart and the Brain
Evolving Role of Exercise, ACE-inhibitors, Interventional and Surgical Options

Dr. Creager
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8:55 a.m. Sleep Apnea: Types, Mechanisms and Clinical Cardiovascular Consequences
A Frequent Condition, but Easily Missed

Dr. Javaheri
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9:15 a.m. LV Non-compaction: A Distinct Genetical Cardiomyopathy?
Perhaps Less Frequent and Less Threatening than Previously Advertised

Dr. Arbustini
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9:35 a.m. Cardio-oncology Evolving into Prime Time Status
Prevention of Anthracycline-induced Cardiotoxicity

Dr. Yeh
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9:55 a.m. Thromboembolism During NSR in Patients with a History of Atrial Fibrillation
Is Left Atrial Appendix Dysfunction Sufficient to Generate the Cloth?

Dr. J. Halperin
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Section XI: Novelties on Therapeutic Strategies

10:25 a.m. The Evolving Science of Stents
Current Status of Bioresorbable Scaffolds: Moving Forward or Backwards?

Dr. Hamm
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10:45 a.m. PAUL DUDLEY WHITE LECTURE 2015
The Historical Path to an Angiotensin Receptor Antagonist-neprilysin Inhibitor
A New and Exciting Pharmacological Approach to the Management of CHF

Dr. Braunwald
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11:15 a.m. Closing Remarks
Dr. Fuster
11:30 a.m. Course Adjournment