An Educational Program

Program Directors:
Robert O. Bonow, M.D., F.A.C.C.
Co-Director, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Chief, Division of Cardiology
Goldberg Distinguished Professor of Cardiology, Northwestern Universiy Feinberg School of Medicine
Chicago, Ill.

Patrick M. McCarthy, M.D., F.A.C.C.
Co-Director, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Chief, Division of Cardiothoracic Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.

David H. Adams, MD
Marie Josee and Henry R. Kravis Professor, Mount Sinai School of Medicine, Chairman, Department of Cardiothoracic Surgery, Mount Sinai Hospital, New York, NY

Patrick T. O'Gara, M.D., F.A.C.C.
Associate Professor of Medicine, Harvard Medical School
Director, Clinical Cardiology
Brigham and Women's Hospital
Boston, Mass.

Faculty:
Keynote Speaker
Alain Carpentier, M.D., Ph.D.
Hospital Europeen Georges Pompidou, Paris,  France

Philipp Bonhoeffer, M.D., F.A.C.C.
Chief of Cardiology
Director of the Cardiac Cathiterizaton Laboratory, Great Ormond Street Hospital, London, U.K.

Jeffrey S. Borer, M.D., F.A.C.C.
Gladys and Roland Harriman Professor of Cardiovascular Medicine, Chief, Division of Cardiovascular Pathophysiology and Chairman, The Howard Gilman Institute for Valvular Heart Diseases, Weill Medical College of Cornell University, New York-Presbyterian Hospital, New York, N.Y.

Blase Anthony Carabello, M.D., F.A.C.C.
Vice-Chairman, Department of Medicine, DeBakey Veterans Affairs Medical Center, Houston, Texas

Tirone E. David, M.D., F.A.C.C.
Head, Division of Cardiovascular Surgery, Toronto General Hospital, University Health Network
MD, Professor of Surgery, Toronto, Canada

Ted Feldman, M.D., F.A.C.C.
Professor of Medicine
Northwestern University Feinberg School of Medicine
Director, Cardiac Catherization Laboratory, Evanston Northwestern Healthcare, Evanston, Ill.

A. Marc Gillinov, M.D., F.A.C.C.
Surgical Director for the Center for Atrial Fibrilation, The Cleveland Clinic, Cleveland, Ohio

Thomas Gleason, M.D., F.A.C.C.
Director, Thoracic Aortic Surgery Program, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Assistant Professor of Surgery
Northwestern University
Feinberg School of Medicine
Chicago, Ill.

Catherine Otto, M.D., F.A.C.C.
Director, Training Programs in Cardiovascular Disease
University of Washington Medical Center, Seattle, Wash.

Nalini M. Rajamannan, M.D., F.A.C.C.
Director, Center for Heart Valve Disease, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Assistant Professor of Medicine, Northwestern Universtiy
Feinberg School of Medicine
Chicago, Ill.

Pravin Shah, M.D.,F.A.C.C.
Chair, Heart Valve Center, Hoag Heart and Vascular Institute, Newport Beach, CA

2006 Heart Valve Summit

Directed by Robert O. Bonow, M.D., F.A.C.C, Patrick M. McCarthy, M.D., F.A.C.C., David H. Adams, M.D., F.A.C.C., and Patrick T. O'Gara, M.D., F.A.C.C.

June 15-17, 2006
Renaissance Chicago Hotel

Schedule

| THURSDAY | FRIDAY | SATURDAY |

Thursday, June 15

07:00 a.m. Registration and Continental Breakfast

07:50 a.m.Introduction and Welcome — Course Directors
Aortic Valve Disease 1 — Dr. Bonow, Moderator            
                                       
08:00 a.m.Aortic Stenosis:  Natural History and Clinical Evaluation — Dr. Otto                                                                                 

08:35 a.m. Calcific Aortic Stenosis:  Novel Cellular Targets for Therapy—Dr. Rajamannan                              

09:10 a.m.Aortic Stenosis: Indications for Aortic Valve Replacement—Dr. O’Gara                              

09:45 a.m.Refreshment Break/ Exhibits Open

10:15 a.m. Selection of the Optimal Aortic Valve Prosthesis—Dr. Gillinov                                

10:50 a.m. Novel Surgical Approaches to Aortic Valve Disease—Dr. David                                  

11:25 a.m. Mechanisms of Left Ventricular Dysfunction in Aortic Valve Disease: Implications for Therapy—Dr. Borer                   

12:00 noon Panel discussion—Drs. Otto, Rajamannan, O’Gara, Gillinov, David and Borer                                  

12:30 p.m.  Lunch/ Exhibits Open

Aortic Valve Disease 2—Moderator: Dr. McCarthy                                                   

1:30 p.m. Natural History of Aortic Regurgitation and Clinical Evaluation—Dr. Bonow                                  

2:05 p.m. Timing of Surgery for Aortic Regurgitation—Dr. Carabello                                  

2:40 p.m. Approach to Surgical Treatment of Disease of the Aortic Root and Ascending Aorta—Dr. Gleason                                

3:15 p.m. Refreshment Break/Exhibits Open

3:40 p.m. Debate: Patients Undergoing Coronary Revascularization Surgery with Mild Aortic Stenosis Should have Aortic Valve Replacement Too—Pro: Dr. Gleason—Con: Dr. Otto      

4:10 p.m. Debate: Patient-Prosthesis Mismatch Contributes Importantly to Postoperative Morbidity Following Aortic Valve Replacement
Pro: Dr. David—Con: Dr. Gillinov               

4:40 p.m.Debate: Vasodilator Therapy is Indicated in Asymptomatic Patients with Chronic Severe Aortic Regurgitation—Pro: Dr. Borer
—Con: Dr. Carabello                  

5:10 p.m. – 6:00 p.m. Networking Reception with Faculty and Participants

Friday, June 16
07:00 a.m. Continental Breakfast — Update on 2006 ACC/AHA Valvular Heart Disease Guidelines—Dr. O’Gara, moderator                     

08:00 a.m. Overview of the 2006 Guidelines: Areas of Emphasis—Dr. Bonow— Guidelines for Valvular Heart Disease: What’s New   
                                                              
08:25 a.m. Aortic Stenosis—Dr. Otto                                  

08:45 a.m. Aortic Regurgitation—Dr. O’Gara                                           

09:05 a.m. Mitral Regurgitation—Dr. Carabello                                       

09:25 a.m. Intraoperative Echocardiography—Dr. Shah                                  

09:45 a.m. Panel Discussion: What the Guidelines Do and Don’t Tell Us—Dr. O’Gara, moderator—Drs. Bonow, Otto, Carabello and Shah                                                             

10:10 a.m. Refreshment Break/Exhibits Open

Mitral Valve 1—Dr. Adams, moderator

10:40 a.m. Degenerative Mitral Valve Disease May Not be Degenerative: Cellular Mechanisms—Dr. Rajamannan                              

11:05 a.m. Understanding Surgery for Degenerative Mitral Valve Disease—Dr. Adams                                

11:30 a.m. Ischemic Mitral Regurgitation—Dr. McCarthy                                  

11:55 a.m. Panel Discussion—Drs. Adams, Rajamannan and McCarthy                                 

12:15 p.m.  Lunch 
Keynote Address: The Foundations of Nonthrombogenic Valvular Heart Surgery—Dr. Carpentier                                           
Mitral Valve 2—Dr. McCarthy, moderator                                                                                            

1:45 p.m. Medical Decision Making: Mitral Valve Endocarditis—Dr. O’Gara                                 

2:10 p.m. Surgical Management of Mitral Valve Endocarditis—Dr. Adams
                                                                                            
2;35 p.m. How to Assess Severity of Mitral Regurgitation Quantitatively by Echocardiography—Dr. Otto                                                           

3:00 p.m. The Role of Atrial Fibrillation Surgery in Valve Surgery—Dr. McCarthy                                   

3:35 p.m. Refreshment Break/Exhibits Open

4:00 p.m. Debate: Patients with Asymptomatic Moderate Mitral Regurgitation Should Undergo Mitral Valve Repair—Pro: Dr. David—Con: Dr. Borer                               

4:30 p.m. Debate: Mitral Regurgitation in Patients with Cardiomyopathy is a Surgical Disease—Pro: Dr. Adams—Con: Dr. Bonow                                                      

5:00 p.m. – 5:30 p.m.  Debate: Statin Therapy is Indicated to Delay Progression of Valvular Heart Disease—Pro: Dr. Rajamannan—Con: Dr. O’Gara                              

Saturday, June 17

07:00 a.m. Continental Breakfast

07:00 a.m. Breakfast Session: Tricks and Traps of Valve Repair Wet Lab—Dr. Carpentier                                                                    

08:30 a.m. Refreshment Break/Exhibits Open

Percutaneous Approaches to Valvular Heart Disease—Dr. Adams, moderator                                          

08:45 a.m. Evolving Data on Percutaneous Approaches to Treatment of Pulmonic and Aortic Valve Disease—Dr. Bonhoeffer                                                                   

09:30 a.m. Percutaneous Approaches to Mitral Valve Disease—Dr. Feldman                                   

10:15 a.m. Percutaneous Approaches to Tricuspid Valve Disease—Dr. McCarthy                                   

10:35 a.m. Debate: The Future of Mitral Valve Repair is Percutaneous—Pro: Dr. Feldman—Con: Dr. Adams                                

11:05 a.m. Panel Discussion—Drs. Bonhoeffer, Feldman, McCarthy and Adams                                     

11:25 a.m. Post Script

11:35 a.m. Adjourn

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