Study Shows Adverse Effects of Long-Term Alcohol Consumption on BP, BMI
In terms of a link between moderate alcohol consumption and lower coronary heart disease (CHD) risk, the study authors note that given the results from this and other studies, it "seems unlikely that if moderate alcohol consumption is causally related to lower CHD risk this is mediated via HDLc or fibrinogen." Instead they suggest that improved insulin sensitivity might mediate a potential beneficial effect, but that would need to be tested. They also highlighted the "surprising" results in the IV analyses showing a possible benefit of alcohol consumption on triglyceride levels. "Recent evidence suggests that cholesterol in remnants, rather than triglyceride levels per se causes greater CHD, and our result regarding triglyceride levels may be a proxy for remnant cholesterol as the two are highly correlated," they said. Further validation of these results, however, is necessary. "We accept that our finding related to this outcome should be treated with caution unless it is replicated," they said.
Keywords: Ethanol, Lipids, Coronary Disease, Blood Pressure, Insulin Resistance, Glucose, Cholesterol, Body Mass Index, Fibrinogen, Hypertension
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