Simvastatin With or Without Ezetimibe in Familial Hypercholesterolemia - ENHANCE — Presented at SCAI-ACC i2 Summit/ACC 2008


The goal of this trial was to compare the mean change in the intima-media thickness (IMT) measured at three sites in the carotid arteries between patients with heterozygous familial hypercholesterolemia (HeFH) treated with ezetimibe/simvastatin 10/80 mg versus patients treated with high-dose simvastatin 80 mg alone, over a 2-year period.