Endocrine and Renal Effects of Nifedipine Gastrointestinal Theraputic System in Patients With Essential Hypertension: Results of a Multicenter Trial - MATH


The MATH trial was an observational study to evaluate clinical efficacy, safety, and effects on metabolic parameters of a once daily nifedipine gastrointestinal therapeutic system (GITS) in hypertensive patients. Also, the MATH trial was designed to specifically analyze the subgroups of patients with diabetes and obesity for adverse effects of therapy on serum lipids and glucose measurements.