Microalbuminuria, Cardiovascular, and Renal Outcomes - Heart Outcomes Prevention Evaluation - MICRO-HOPE


The MICRO-HOPE was a substudy of the HOPE study. It was a prospective, randomized, double-blind, placebo-controlled, multicenter trial with a two-by-two factorial design, designed to assess the value of ramipril and vitamin E in preventing diabetic nephropathy in diabetic patients with microalbuminuria, and the development of microalbuminuria in diabetic patients not presenting with this condition at baseline.