Physicians' Health Study II - PHS II — Presented at AHA 2008


Although data from basic science and observational studies suggests a possible beneficial effect of antioxidants, especially vitamin C and E, in the primary prevention of cardiovascular events, there are no or conflicting data from randomized controlled trials on this topic. Accordingly, the PHS II trial was designed to assess the role of vitamin C and E supplementation in the prevention of cardiovascular events in low-risk male physicians.