TNK-Tissue Plasminogen Activator Compared With Front-Loaded Tissue Plasminogen Activator in Acute Myocardial Infarction - TIMI 10B


The Thrombolysis in Myocardial Infarction 10B (TIMI 10B) trial was a multicenter, randomized phase II dose-ranging trial in patients with acute ST-segment elevation myocardial infarction (MI) designed to compare prospectively the angiographic efficacy and safety of several doses of tumor necrosis factor-tissue plasminogen activator (TNK-tPA) with tPA.