Study of Heart and Renal Protection - SHARP

Description:

Studies on low-density lipoprotein (LDL) lowering in patients with chronic kidney disease, but no overt coronary disease, have been inconclusive. The current trial sought to compare outcomes after randomization to simvastatin/ezetimibe or placebo in patients with chronic kidney disease (CKD) (estimated glomerular filtration rate [eGFR] < 30 ml/min).