The Trials of Hypertension Prevention, Phase II - TOHP II


TOHP II was a multicenter, randomized trial with a 2x2 factorial design, designed to test the efficacy of interventions to promote weight loss, sodium reduction, and the combination of weight loss and sodium reduction in decreasing diastolic blood pressure (BP), systolic BP, and the incidence of hypertension during a three- to four-year follow-up period in moderately overweight men and women with a high-normal level of diastolic BP.