Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy - MADIT-CRT

Description:

Currently, an implantable cardioverter defibrillator (ICD) is indicated for primary prevention in patients with ischemic (ICM) or nonischemic cardiomyopathy (NICM), with a left ventricular ejection fraction (LVEF) <35%, despite optimal medical management. Cardiac resynchronization therapy (CRT) with or without an ICD (CRT-D) is indicated for symptom improvement in patients with chronic systolic heart failure, with prolonged intraventricular conduction delay (QRS duration ≥120 ms), and ...