The Utility of Cardiac Biomarkers, Tissue Velocity and Strain Imaging, and Cardiac Magnetic Resonance Imaging in Predicting Early Left Ventricular Dysfunction in Patients With Human Epidermal Growth Factor Receptor II–Positive Breast Cancer Treated With Adjuvant Trastuzumab Therapy

Study Questions:

What is the predictive value of cardiac biomarkers, tissue velocity (TVI) and strain imaging, and cardiac magnetic resonance imaging to identify early left ventricular (LV) dysfunction in human epidermal growth factor receptor II–positive breast cancer patients treated with trastuzumab in the adjuvant setting?