Use of Amino-Terminal Pro–B-Type Natriuretic Peptide to Guide Outpatient Therapy of Patients With Chronic Left Ventricular Systolic Dysfunction

Study Questions:

Does targeting N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels to <1000 pg/ml improve outcomes compared with standard optimal care (SOC) in adults with systolic heart failure (HF)?