Factors Contributing to the Lower Mortality With Ticagrelor Compared With Clopidogrel in Patients Undergoing Coronary Artery Bypass Surgery

Study Questions:

In the PLATO (Platelet Inhibition and Patient Outcomes) trial, patients who were assigned to ticagrelor and underwent coronary artery bypass graft surgery (CABG) had significantly lower total and cardiovascular mortality compared with those assigned to clopidogrel. What are the differences in specific causes of post–CABG deaths in the PLATO trial?