American College of Cardiology

TAYLOR ET AL., 34th BETHESDA CONFERENCE: Can Atherosclerosis Imaging Techniques Improve the Detection of Patients at Risk for Ischemic Heart Disease?
J Am Coll Cardiol 2003;41:11:1855-917

BETHESDA CONFERENCE REPORT
34th Bethesda Conference: Can Atherosclerosis Imaging Techniques Improve the Detection of Patients at Risk for Ischemic Heart Disease?¹

Richard C. Pasternak, MD, FACC, Co-Chair, Jonathan Abrams, MD, FACC, Co-Chair, Philip Greenland, MD, FACC, Lynn A. Smaha, MD, PHD, FACC, Peter W. F. Wilson, MD, Nancy Houston-Miller, RN, BSN


Figure 2.

Figure 2. Influence of disease prevalence on predictive accuracy of a typical diagnostic strategy. When used in a population with low disease prevalence, such as an asymptomatic population undergoing cardiovascular screening, even a test with excellent sensitivity (Sens) and specificity (Spec) will yield a poor positive predictive accuracy owing to a larger number of false-positive (FP) than true-positive (TP) results. CAD = coronary artery disease. Reprinted with permission from Gheorghiade and Bonow (43).