GRUNDY
ET AL., Assessment of Cardiovascular Risk
J Am Coll Cardiol 1999;34:1348--59
AHA/ACC
Scientific Statement: Assessment of Cardiovascular Risk
by Use of Multiple-Risk-Factor Assessment Equations
A
Statement for Healthcare Professionals From the American
Heart Association and the American College of Cardiology
X.
Severity of Major Risk Factors
Framingham
scoring takes into account gradations in risk factors
when estimating absolute risk. The scoring does not adequately
account for severe abnormalities of risk factors, eg,
severe hypertension, severe hypercholesterolemia, or heavy
cigarette smoking. In such cases, Framingham scores can
underestimate absolute risk. This underestimation is particularly
evident when only 1 severe risk factor is present. Thus,
heavy smoking31
or severe hypercholesterolemia32
can lead to premature CHD even when the summed score for
absolute risk is not high. Likewise, the many dangers
of prolonged, uncontrolled hypertension are well known.
These dangers underscore the need to control severe risk
factors regardless of absolute short-term risk estimates.
Copyright
© 2000 by The American Heart Association, Inc.
and
The American College of Cardiology
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