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Blomström-Lundqvist ET AL., MANAGEMENT OF PATIENTS WITH Supraventricular Arrhythmias
J Am Coll Cardiol 2003;42:1493–531

ACC/AHA/ESC Guidelines for the Management of Patients With Supraventricular Arrhythmias

A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias)


I. INTRODUCTION

A. Organization of Committee and Evidence Review

Supraventricular arrhythmias are a group of common rhythm disturbances. The most common treatment strategies include antiarrhythmic drug therapy and catheter ablation. Over the last decade, the latter has been shown to be a highly successful and often curative intervention. With the advent of new therapeutic interventions and sophisticated mapping tools, even very complex arrhythmias may be cured. To facilitate and optimize the management of patients with supraventricular arrhythmias, the ACCF, the AHA, and the ESC created a committee to establish guidelines for better management of these heterogeneous tachyarrhythmias. This document summarizes the management of patients with supraventricular arrhythmias with recommendations for diagnostic procedures as well as indications for antiarrhythmic drugs and/or nonpharmacologic treatments.

The panel was composed of physicians and scientists at university and community hospitals. Members were selected to represent experts from different European countries and from the United States and to include members of associations or working groups whose activities and fields of interest were related to the topic of the writing committee, including the ESC Working Groups on Arrhythmias, Cardiac Pacing, and Grown-Up Congenital Heart Diseases and the North American Society of Pacing and Electrophysiology (NASPE-Heart Rhythm Society). The writing committee was composed of six members representing the ACCF and the AHA, four members representing the ESC, and one member representing NASPE. The writing committee was chosen on the basis of willingness and availability to participate actively in meetings and the production of the final manuscript. Writing groups are specifically charged to perform a formal literature review, weigh the strength of evidence for or against a particular treatment or procedure, and estimate expected health outcomes where data exist. Patient-specific modifiers, comorbidities, and issues of patient preference that might influence the choice of particular tests or therapies are considered, as are frequency of follow-up and cost effectiveness. In controversial areas, or with regard to issues without evidence other than usual clinical practice, a consensus was achieved by agreement of the expert panel after thorough deliberations.

This document was peer reviewed by two official external reviewers representing the American College of Cardiology Foundation, two official external reviewers representing the American Heart Association, and two official external reviewers representing the European Society of Cardiology. The North American Society for Pacing and Electro- physiology-Heart Rhythm Society assigned one organiza- tional reviewer to the guideline. In addition, 37 external content reviewers participated in the review representing the ACC/AHA Task Force on Practice Guidelines, the ESC Committee for Practice Guidelines, the ACCF Electro- physiology Committee, the AHA ECG/Arrhythmias Committee, the ESC Working Group on Arrhythmias, and the ESC Task Force on Grown-Up Congenital Heart Disease. See Appendix 2 for the names of all reviewers.

The document was approved for publication by the governing bodies of the ACCF, AHA, and ESC. These guidelines will be reviewed annually by the ESC and the ACC/AHA Task Force on Practice Guidelines and will be considered current unless they are revised or withdrawn from distribution. The ACC/AHA/ESC Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Tachycardias conducted a comprehensive review of the relevant literature. Literature searches were conducted in the following databases: PubMed/Medline, EMBASE, the Cochrane Library (including the Cochrane Database of Systematic Reviews and the Cochrane Controlled Trials Registry), and Best Evidence. Searches were limited to English language sources and to human subjects. The references selected for this document are exclusively peer-reviewed papers that are representative but not all-inclusive. Recommendations are evidence-based and derived primarily from published data. The level of evidence was ranked as follows: Level A (highest): derived from multiple randomized clinical trials;

Level B (intermediate): Data are based on a limited number of randomized trials, nonrandomized studies, or observational registries;
Level C (lowest): Primary basis for the recommendation was expert consensus.

Recommendations follow the format of previous ACC/AHA guidelines for classifying indications, summarizing both the evidence and expert opinion.

Class I: Conditions for which there is evidence and/or general agreement that a given procedure or treatment is useful and effective.

Class II: Conditions for which there is conflicting evi- dence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
Class IIa: Weight of evidence or opinion is in favor of usefulness/efficacy.
Class IIb: Usefulness/efficacy is less well established by evidence or opinion.

Class III: Conditions for which there is evidence and/or general agreement that the procedure or treatment is not useful/effective and in some cases may be harmful.

B. Contents of These Guidelines—Scope

The purpose of this joint ACC/AHA/ESC document is to provide clinicians with practical and authoritative guidelines for the management and treatment of patients with supraventricular arrhythmias (SVA). These include rhythms emanating from the sinus node, from atrial tissue (atrial flutter), and from junctional as well as reciprocating or accessory pathway-mediated tachycardia. This document does not include recommendations for patients with atrial fibrillation (AF) [see ACC/AHA/ESC Guidelines for the Management of Patients With Atrial Fibrillation (1)] or for pediatric patients with supraventricular arrhythmias. In this document, SVT is used to describe re-entrant arrhythmias involving the atrioventricular (AV) junction (atrioventricular nodal reciprocating tachycardia [AVNRT]), atrium [atrial tachycardia (AT)], or AV-reciprocating rhythms [atrioventricular reciprocating tachycardia (AVRT)]). For our purposes, the term “supraventricular arrhythmia” refers to all types of supraventricular arrhythmias, excluding AF, as opposed to SVT, which includes AVNRT, AVRT, and AT.

These guidelines first present a review of the definition, public health, epidemiology, general mechanisms, and clinical characteristics of SVT. The management of each specific tachycardia is then presented, including a review of the existing literature relating to drug versus catheter ablative therapy. The treatment algorithms include pharmacologic and nonpharmacologic antiarrhythmic approaches thought to be most appropriate for each particular condition. Overall, this is a consensus document that includes evidence and expert opinions from several countries. The pharmacologic and

Copyright © 2004 by the American College of Cardiology Foundation and the American Heart Association, Inc.

 

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