Table of Contents Print a PDF References Figures & Tables
< Previous Next >
FUSTER ET AL., ACC/AHA/ESC GUIDELINES FOR THE MANAGEMENT OF PATIENTS WITH ATRIAL FIBRILLATION
J Am Coll Cardiol 2001;38:1266i-1xx

ACC/AHA/ESC Guidelines for the Management of Patients with Atrial Fibrillation

III. Classification

AF has a heterogeneous clinical presentation, occurring in the presence or absence of detectable heart disease or related symptoms. Various classification systems have been proposed for AF. One scheme is based on the ECG presentation (1-3). Another is based on epicardial (5) or endocavitary recordings or noncontact mapping of atrial electrical activity. Several clinical classification schemes have also been proposed, but none fully accounts for all aspects of AF (6-9). To be clinically useful, a classification system must be based on a sufficient number of features and carry specific therapeutic implications.

An episode of AF may be self-limited or require medical intervention for termination. Over time, the pattern of AF may be defined in terms of the number of episodes, duration, frequency, mode of onset and possible triggers, and response to therapy, but these features may be impossible to discern when AF is first encountered in an individual patient. Although the pattern of the arrhythmia can change over time, it may be of clinical value to characterize the arrhythmia at a given moment.

Assorted labels have been used to describe the pattern of AF, including acute, chronic, paroxysmal, intermittent, constant, persistent, and permanent, but the vagaries of definitions make it difficult to compare studies of AF in terms of the effectiveness of therapeutic strategies based on these designations. The classification scheme recommended in this document represents a consensus driven by a desire for simplicity and clinical relevance.

The clinician should distinguish a first-detected episode of AF, whether or not it is symptomatic or self-limited, recognizing that there may be uncertainty about the duration of the episode and about previous undetected episodes (Figure 3). When a patient has had 2 or more episodes, AF is considered recurrent. If the arrhythmia terminates spontaneously, recurrent AF is designated paroxysmal; when sustained, AF is designated persistent. In the latter case, termination with pharmacological therapy or electrical cardioversion does not change the designation. Persistent AF may be either the first presentation of the arrhythmia or the culmination of recurrent episodes of paroxysmal AF. The category of persistent AF also includes cases of long-standing AF (e.g., greater than 1 year) in which cardioversion has not been indicated or attempted, usually leading to permanent AF (Figure 3).

The terminology defined in the preceding paragraph applies to episodes of AF that lasts more than 30 seconds and that are unrelated to a reversible cause. Secondary AF that occurs in the setting of acute myocardial infarction (MI), cardiac surgery, pericarditis, myocarditis, hyperthyroidism, pulmonary embolism, pneumonia, or acute pulmonary disease is considered separately, because AF is less likely to recur once the precipitating condition is resolved. In these settings, AF is not the primary problem, and treatment of the underlying disorder concurrently with management of the episode of AF usually results in termination of the arrhythmia without recurrence.

The term "lone AF" has been variously defined but generally applies to young individuals (under 60 years of age) without clinical or echocardiographic evidence of cardiopulmonary disease (10). These patients have a favorable prognosis with respect to thromboembolism and mortality. As time goes by, however, patients move out of the lone AF category by virtue of aging or the development of cardiac abnormalities such as enlargement of the left atrium (LA), and the risks of thromboembolism and mortality rise accordingly. Lone AF is distinguished from other forms of idiopathic AF because of the criteria of patient age and the absence of identified cardiovascular pathology. By convention, the term nonvalvular AF is restricted to cases in which the rhythm disturbance occurs in the absence of rheumatic mitral valve disease or a prosthetic heart valve.

 

Copyright © 2001 by the American College of Cardiology, American Heart Association, Inc., and the European Society of Cardiology
Published by Elsevier Science Inc.

Back to Top | | Copyright © 2008 American College of Cardiology
Heart House | 2400 N Street, NW | Washington, DC 20037