http://www.acc.org/Feed?clinicalTopicID=229f7074-fb00-4bea-a844-8ef25973206d Clinical Topic Feed: EP Basic Science en /Latest-in-Cardiology/Articles/2026/08/29/08/48/mon-315am-comboep-esc-2026 Three Hot Line trials from ESC Congress 2026 – ASPIRED, DANISH-CRT, and His-Alternative II – test 14-day ECG monitoring in patients with unexplained syncope, compare cardiac resynchronization therapy (CRT) modalities, and assess targeted left ventricular lead placement at the site of latest electrical activation in patients with heart failure and prolonged QRS. 1788168300000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/08/10/15/19/High-Pediatric-Ablation-Success Acute ablation success in pediatric patients was high across a range of center and operator volumes, with high-volume sites demonstrating the greatest likelihood of success for complex substrates, according to a recent study published in JACC: Advances. 1786386480000 Articles and Stories /Latest-in-Cardiology/Articles/2026/07/07/14/25/Safety-of-Antiarrhythmic-Agents-in-Breastfeeding-Women According to the American Academy of Pediatrics (APA) and the World Health Organization (WHO), exclusive breastfeeding is recommended for the first 6 months of infant life, with continuation up to 2 years or as long as mutually desired by the lactating individual and infant. 1783940280000 Articles and Stories /Latest-in-Cardiology/Articles/2026/05/12/15/21/eagles-eye-view-13may2026 In this week’s View, Dr. Eagle examines the role of rhythm control in improving moderate-to-severe and severe secondary tricuspid valve regurgitation. 1778679000000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/05/04/11/24/AVANT-GUARD The likelihood of recurrence of atrial arrhythmia in patients with persistent atrial fibrillation (AFib) was lower for those who received pulsed field ablation (PFA) as first-line therapy when compared to those who first tried antiarrhythmic drug (AAD) therapy, according to results from the AVANT-GUARD trial published April 25 in NEJM. 1777994460000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/04/22/11/23/LEFT-BUNDLE-CRT Among patients who were eligible for CRT, left bundle branch area pacing (LBBAP) was not found to be noninferior to biventricular pacing (BiVP) in the intention-to-treat analysis, according to results from the LEFT-BUNDLE-CRT trial published April 14 in EHJ. 1776865440000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/03/24/18/20/New-CCG-Isolated-Left-to-Right-Shunt-Lesions-in-Pediatric-Patients Outpatient management of isolated left-to-right shunt lesions in pediatric patients with congenital heart disease is the focus of a new 2026 ACC Concise Clinical Guidance report. 1774533600000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/03/18/17/30/HeartSync-LBBP-and-PhysioSync-HF-Comparing-Conduction-System-Pacing-vs-BiVP-in-Patients-With-HFrEF-and-LBBB Two studies recently published in JAMA Cardiology present conflicting findings in comparing conduction system pacing (CSP), such as left bundle-branch pacing (LBBP), and biventricular pacing (BiVP) in patients with heart failure with reduced ejection fraction (HFrEF) and left bundle-branch block (LBBB). 1773855960000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/04/14/11/eagles-eye-view-04mar2025 In this week’s View, Dr. Eagle looks at increased one-year mortality in younger patients undergoing transcatheter aortic valve replacement (TAVR). 1772636400000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/02/26/18/18/20-Year-Outcomes Twenty years after pulmonary vein isolation (PVI) during catheter ablation, stable sinus rhythm was maintained in a quarter of patients with symptomatic drug-refractory paroxysmal atrial fibrillation (PAF), including those taking antiarrhythmic drugs and those who had multiple ablation procedures, according to findings from a study published Feb. 17 in JACC: Clinical Electrophysiology. 1772131380000 Articles and Stories