http://www.acc.org/Feed?clinicalTopicID=2e96633a-1c99-4f33-9eda-83554d60f058 Clinical Topic Feed: Interventions and Coronary Artery Disease en /Latest-in-Cardiology/Articles/2026/06/08/10/20/Optimizing-Dual-Antiplatelet-Therapy The TUXEDO-2 (Ultrathin Strut vs. Xience in a Diabetic Population With Multivessel Disease 2—India Study) trial demonstrated that among patients with diabetes mellitus and multivessel coronary artery disease undergoing percutaneous coronary intervention (PCI)... 1781024040000 Articles and Stories /Latest-in-Cardiology/Articles/2026/06/01/01/Journal-Wrap The hottest research from various peer-reviewed journals – handpicked weekly by the ACC. 1780315620000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/05/04/11/24/ORBITA-Analysis Patients with lower microvascular resistance (MVR) saw greater placebo-controlled benefit from PCI, according to a retrospective analysis of the ORBITA trial published April 29 in JACC: Cardiovascular Interventions. 1778087340000 Articles and Stories /Latest-in-Cardiology/Articles/2026/04/27/19/07/ACC26-Coronary-Interventional-Trials Late-breaking clinical trials presented at ACC.26 focusing on coronary interventions included several looking at intravascular guidance in complex, high-risk procedures (IVUS-CHIP), bifurcation lesions (DKCRUSH VIII), and unprotected left main PCI (OPTIMAL). 1777570260000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/04/28/20/06/noble No significant difference was observed in all-cause mortality at 10 years between PCI and CABG in patients with unprotected left main coronary artery disease (CAD) and no additional complex lesions, according to the final results of the NOBLE study published April 4 in The Lancet. 1777412340000 Articles and Stories /Latest-in-Cardiology/Articles/2026/04/21/15/23/ACC26-Structural-Intervention-Trials-Offer-Viable-Options Late-breaking clinical trials presented at ACC.26 focusing on structural interventions included the PROTECT H2H trial comparing two embolic protection devices (EPDs) in patients undergoing transcatheter aortic valve implantation (TAVI), the PRO-TAVI trial comparing a strategy of routine PCI with a deferred approach... 1776939000000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/25/21/27/sun-4pm-protavi-acc-2026 Older patients with coronary artery disease (CAD) for whom PCI was deferred until after TAVI had similar outcomes as those for whom it was not deferred, according to findings from the PRO-TAVI study presented in a Late-Breaking Clinical Trial session... 1774818600000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/18/00/50/eagles-eye-view-18mar2025 In this week’s View, Dr. Eagle looks at data from the STS/ACC TVT Registry on off label transcatheter valve interventions that demonstrate reduced residual tricuspid regurgitation (TR) and improved quality of life. 1773842400000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/03/10/16/54/RENOVATE-COMPLEX-PCI-Benefit-With-Intravascular In the multicenter open-label superiority trial, Joo Myung Lee, MD, MPH, PhD, FACC, et al., randomized 1,639 patients (mean age 66; 20% women) with complex coronary artery lesions across 20 hospitals in South Korea 2:1 to either intravascular imaging-guided PCI (n=1,092) or angiography-guided PCI (n=547). Of the overall cohort, 49% presented with stable ischemic heart disease and 51% with an acute coronary syndrome (ACS). Thirty-one percent had three or more characteristics of complex coronary artery lesions in the target lesion. The most common was long coronary lesion, followed by multivessel PCI, true bifurcation lesion and chronic total occlusion. 1773162180000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/04/12/02/Extended-DAPT-in-Multivessel-CAD The DAPT-MVD (Dual Antiplatelet Therapy in Patients With Coronary Multi-Vessel Disease) trial was a multicenter, randomized, open-label study in China designed to assess whether extending dual antiplatelet therapy (DAPT) beyond 12 months provides additional benefit for patients with multivessel coronary artery disease (CAD)... 1772647140000 Articles and Stories