http://www.acc.org/Feed?clinicalTopicID=45d25f86-5c8b-42a6-818b-c3998baad19a Clinical Topic Feed: Lipid Metabolism en /Latest-in-Cardiology/Articles/2026/10/09/15/06/AMUNDSEN Lipid lowering after acute myocardial infarction (MI) is central to secondary prevention, but stepwise therapy may delay LDL-C target attainment. The AMUNDSEN trial, presented at ESC Congress 2026 and simultaneously published in JAMA, assessed whether pre-PCI evolocumab could accelerate LDL-C reduction and improve clinical outcomes. 1791903300000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/01/01/Feature-ESC-Congress-2026 The ACC was live from ESC Congress 2026 in Munich, bringing members the latest cardiovascular science and clinical guidance. Below are standout studies in heart failure (HF), structural heart disease, dyslipidemia and prevention, and more, plus promising news in pulmonary embolism (PE). 1790857080000 Articles and Stories /Latest-in-Cardiology/Articles/2026/09/28/16/16/cardiacast_28sep2026 This episode is part of ACC’s ongoing initiative on implementing the 2026 Dyslipidemia guidelines. 1790612400000 Articles and Stories /Latest-in-Cardiology/Articles/2026/09/25/14/46/cardiacast_25sep2026 This episode is part of ACC’s ongoing initiative to recognize the risks and tackle management of hypertriglyceridemia (HTG) and severe hypertriglyceridemia (sHTG). 1790352000000 Articles and Stories /Education-and-Meetings/Patient-Case-Quizzes/2026/09/22/14/57/Management-of-Severe-Hypertriglyceridemia A 62-year-old man with coronary artery disease with a single coronary stent from 10 years ago presents for follow-up. His other medical history includes former smoking and hypertension, which is currently well managed. 1790089200000 Educational Activities /Latest-in-Cardiology/Articles/2026/09/01/01/Feature-Getting-to-Goals New evidence-based risk assessment and treatment algorithms were introduced in the 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA /AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia. 1788264960000 Articles and Stories /Latest-in-Cardiology/Articles/2026/09/01/01/JACC-in-a-Flash Featured topics and Editors' Picks from all of ACC's JACC Journals. 1788264600000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/29/08/48/sun-1215pm-prevention-esc-2026 The results from two Hot Line trials presented at ESC Congress 2026 hold promise for patients with high blood pressure (BP) at risk of dementia, and for patients with severe hypertriglyceridemia. 1788106500000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/24/12/30/sat-jacc-journals-esc-2026 Several abstracts and e-posters presented at ESC Congress 2026 and simultaneously published across the JACC family of journals highlight the expanding role of precision medicine, novel therapeutics, and advanced risk stratification across cardiovascular care. 1788002340000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/24/12/30/sat-amundsen-esc-2026 First-line evolocumab combined with high-intensity lipid-lowering therapy produced rapid and sustained LDL-C reduction in patients with acute MI undergoing PCI, with more than 80% reaching the guideline recommended target of LDL-C less than 55 mg/dL at one year, said researchers presenting findings from the AMUNDSEN trial at ESC Congress 2026. However, no clinical benefit was detected during the first year of follow-up. 1787992740000 Articles and Stories