http://www.acc.org/Feed?clinicalTopicID=58616d42-1fda-49eb-a3ed-40ba0d5d99c0 Clinical Topic Feed: Chronic Angina en /Latest-in-Cardiology/Articles/2026/11/02/22/45/tues-145pm-pioneer-tct-2026 Noninferiority of angiography-derived fractional flow reserve (angio-FFR) was not met when compared to usual care in patients undergoing PCI, according to results of the PIONEER IV trial, presented at TCT 2026. 1793733600000 Articles and Stories /Latest-in-Cardiology/Articles/2026/11/01/00/11/mon-627pm-pci-stemi-tct-2026 Prolonged perfusion balloon predilation and intracoronary delivery of Nicorandil with the Rx Ryusei perfusion balloon did not significantly reduce slow-flow or no-reflow in patients presenting with STEMI undergoing primary PCI, according to findings from the TomorrowLAND trial presented at TCT 2026. 1793662020000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/26/16/55/sat-fcr2-tct-2026 Two randomized trials published in JACC and presented as Featured Clinical Research at TCT 2026 examine whether scaling back antithrombotic therapy, using short-term anticoagulation rather than dual antiplatelet therapy (DAPT) after left atrial appendage closure (LAAC) and omitting aspirin during primary STEMI in high-risk patients, can limit bleeding while maintaining protection against thrombotic events. 1793559180000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/26/16/55/sat-challenging-cases-tct-2026 New challenging cases presented at TCT 2026 and simultaneously published across the JACC family of journals offer insights into key questions and challenging scenarios in interventional cardiology. 1793558940000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/26/16/55/sat-ai-combo-tct-2026 A mobile app for optimizing STEMI care and use of AI to detect aortic valve calcification on routine noncontrast chest CT are among the innovations being discussed and presented at TCT 2026 and simultaneously published in JACC: Advances. 1793474880000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/28/13/38/eagles-eye-view-28oct2026 n this week’s View, Dr. Eagle looks at a brief report on how cardiac death remains a substantial contributor to on-duty mortality of U.S. firefighters, and how drivers of this trend may not be well identified by the current screening approaches. 1793194860000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/10/20/19/27/Acute-Coronary-Occlusions A significant proportion of patients with NSTEMI had acute coronary occlusions (ACOs), and ACO was associated with worse in-hospital outcomes among patients in the NSTEMI cohort, according to a recent study published in JACC: Cardiovascular Interventions. 1792587600000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/10/20/19/27/Noninfarct-Related-Artery-PCI Noninfarct-related artery (non-IRA) revascularization in patients with STEMI and multivessel coronary artery disease (CAD) increased modestly from 2018 to 2022; however, a majority of patients did not undergo non-IRA PCI within 45 days of primary PCI, according to a recent study published in Circulation: Cardiovascular Interventions. 1792587600000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/16/17/49/Trials-at-ESC Four late-breaking trials, presented at ESC Congress 2026 focused on post-acute coronary syndrome (ACS) antithrombotic therapy. 1792177140000 Articles and Stories /Latest-in-Cardiology/Articles/2026/10/14/12/36/Emerging-Evidence Refractory angina (RA) is an increasing global cardiovascular challenge, affecting approximately 10-15% of patients with coronary artery disease (CAD). RA is defined as persistent anginal symptoms (≥3 months) due to myocardial ischemia despite guideline-directed medical therapy... 1791999300000 Articles and Stories