http://www.acc.org/Feed?clinicalTopicID=677b3288-77e4-47f8-8697-3e2ce6a4dd87 Clinical Topic Feed: Anticoagulation Management en /Latest-in-Cardiology/Articles/2026/08/29/08/48/sun-545am-combo-tavi-esc-2026 Three late-breaking trials presented at ESC Congress 2026 offer new insights into the management of structural heart disease and heart failure (HF), spanning coronary revascularization during TAVI, transcatheter treatment of tricuspid regurgitation, and post-TAVI antithrombotic therapy. Together, the TAVI PCI, ACASA-TAVI and TRIC-I-HF studies provide important evidence to help refine treatment strategies and improve patient outcomes. 1788091440000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/24/12/30/sat-6am-combo-interventional-esc-2026 Interventional science was the focus of a Hot Line Session at ESC Congress 2026, with studies shedding light on milvexian with antiplatelet therapy following an acute coronary event; aspirin omission at the time of primary PCI in STEMI; switching from ticagrelor to prasugrel following PCI in patients with acute coronary syndrome (ACS); clopidogrel vs. extended DAPT after high-risk PCI; and potent antiplatelet therapy in patients with atrial fibrillation (AFib) following myocardial infarction (MI). 1788005340000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/24/12/30/fri-515am-single-af-esc-2026 In patients with atrial fibrillation (AFib) at intermediate risk for stroke, DOAC therapy resulted in a lower risk of stroke, systemic embolism, major bleeding or death from cardiovascular causes at 24 months compared with no anticoagulation. 1787912460000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/08/10/15/19/COMBINE-AF Clinically relevant extracranial bleeding affected approximately one in four patients receiving oral anticoagulation (OAC) for atrial fibrillation (AFib) over two years, potentially providing a more comprehensive measure of bleeding burden than major bleeding alone, according to a recent COMBINE-AF analysis published in Circulation. 1786546740000 Articles and Stories /Latest-in-Cardiology/Articles/2026/08/10/13/07/eagles-eye-view-12aug2026 In this week’s View, Dr. Eagle looks at the wide variation in antithrombotic regimens after valve-in-valve transcatheter aortic valve replacement (TAVR). Next, he examines PARTNER-3, a 7-year study on TAVR versus surgical aortic valve replacement (SAVR) outcomes in low-risk patients. 1786537680000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/08/03/10/06/Wide-Variation-in-Antithrombotic-Regimens There is wide variation in antithrombotic regimens after valve-in-valve (ViV) TAVR and no significant differences in outcomes, according to a study published July 27 in JACC: Cardiovascular Interventions. 1785780360000 Articles and Stories /Latest-in-Cardiology/Articles/2022/01/01/01/01/ACC-Featured-Jobs Ready to explore a new professional opportunity? Browse the list below of featured jobs and take the next step in your career! 1785581280000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/07/28/17/19/OPTIMA-AF Only one month of dual antithrombotic therapy followed by direct oral anticoagulant (DOAC) monotherapy proved to be noninferior in terms of efficacy and superior in terms of bleeding outcomes to the standard 12-month dual antithrombotic therapy post PCI among patients with atrial fibrillation (AFib), according to results of the OPTIMA-AF trial published July 15 in The Lancet. 1785260580000 Articles and Stories /Latest-in-Cardiology/Articles/2026/07/08/14/16/eagles-eye-view-08jul2026 In this week’s View, Dr. Eagle looks at withdrawing guideline-directed medical therapy (GDMT) for patients with atrial fibrillation (AF). 1783520220000 Articles and Stories /Latest-in-Cardiology/Articles/2026/06/29/15/28/Discontinuation-of-Anticoagulation Current guidelines for management of atrial fibrillation (AF) recommend continuation of oral anticoagulation (OAC) following successful catheter ablation of AF for patients deemed at elevated thromboembolic risk. 1782921180000 Articles and Stories