http://www.acc.org/Feed?clinicalTopicID=f66067a7-924e-48e8-8362-69c077adf16b Clinical Topic Feed: Hypertriglyceridemia en /Latest-in-Cardiology/Articles/2026/03/25/21/27/mon-830am-essence-acc-2026 In patients with moderate hypertriglyceridemia, significant reductions in triglyceride and remnant cholesterol levels with olezarsen, on top of standard-of-care lipid-lowering therapy, did not translate into a significant change from baseline in noncalcified coronary plaque volume (NCPV), according to results from Essence-CTA, a substudy of the Essence-TIMI 73b trial, presented during a Late-Breaking Clinical Trial session at ACC.26 in New Orleans and simultaneously published in Circulation. 1774877580000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/18/00/50/eagles-eye-view-18mar2025 In this week’s View, Dr. Eagle looks at data from the STS/ACC TVT Registry on off label transcatheter valve interventions that demonstrate reduced residual tricuspid regurgitation (TR) and improved quality of life. 1773842400000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/03/13/15/20/ACC-AHA-Release-New-Clinical-Guideline-For-Managing-Dyslipidemia The new ACC/AHA Guideline on the Management of Dyslipidemia offers a comprehensive “one-stop shop” for addressing the evaluation, management and monitoring of individuals with dyslipidemias, including high blood cholesterol, hypertriglyceridemia, and elevated lipoprotein(a) (Lp[a]). 1773415860000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/01/01/Cover-Story-The-Adipokine-Hypothesis Fourteen hours a day, nearly every day for a year. That's how long it took Milton Packer, MD, FACC, to write his groundbreaking hypothesis connecting adipokines and visceral adiposity to heart failure with preserved ejection fraction (HFpEF). 1772371140000 Articles and Stories /Latest-in-Cardiology/Articles/2026/03/01/01/JACC-in-a-Flash Featured topics and Editors' Picks from all of ACC's JACC Journals. 1772370600000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/02/17/14/32/Unpacking-CV-Nutritional-Controversies-in-2026 In response to increased controversy over what makes up a healthy diet, a recent JACC: Advances State-of-the-Art Review dives into the evidence both for and against several controversial foods and provides recommendations based on the available literature on cardiovascular health and outcomes. 1771434420000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2026/02/02/20/04/MESA Early initiation of hormone replacement therapy (HRT) may benefit all racial/ethnic groups except Chinese women, and Chinese women with metabolic syndrome or elevated triglycerides may have increased risk of adverse cardiovascular outcomes with HRT, according to research from the MESA published Jan. 27 in JACC: Advances. 1770129180000 Articles and Stories /Latest-in-Cardiology/Clinical-Trials/2025/09/19/18/14/Essence-TIMI-73b The Essence-TIMI 73b trial demonstrated that olezarsen, compared with placebo, significantly reduced triglyceride levels in patients with moderate hypertriglyceridemia and elevated cardiovascular risk. 1758568260000 Articles and Stories /Latest-in-Cardiology/Articles/2025/08/01/01/JACC-in-a-Flash Featured topics and Editors' Picks from all of ACC's JACC Journals. 1754050200000 Articles and Stories /Latest-in-Cardiology/Journal-Scans/2025/05/28/13/17/New-Research-Adds-to-Growing-Evidence New original research – part of a special JACC focus issue on lipids – adds to the growing body of evidence surrounding lipoprotein(a) (Lp[a]) and its contribution as an independent causal risk factor for cardiovascular disease and aortic stenosis. 1748464020000 Articles and Stories