Below are the most popular ACC.org content items of 2025.

Top 10 New Guidelines and Clinical Policy Articles

1. ACC/AHA Guideline Addresses Prevention, Detection, Evaluation and Management of High BP
2. ACC/AHA Issue New Acute Coronary Syndromes Guideline
3. ACC/AHA Guideline Addresses Management of Congenital Heart Disease in Adults
4. ACC's First Concise Clinical Guidance Focuses on Evaluation and Management of Cardiogenic Shock
5. ACC Concise Clinical Guidance Addresses Evaluation and Management of Pericarditis
6. New Guidance Addresses Competitive Sports Participation For Athletes With CV Abnormalities
7. ACC Concise Clinical Guidance Report 'Weighs In' on Medical Weight Management For Optimizing CV Health
8. ACC Concise Clinical Guidance Addresses Evaluation and Management of ATTR-CM
9. ACC Scientific Statement Details Role of Inflammation in CVD
10. Training Statement Outlines Core Competencies, Training Requirements For Advanced CV Imaging

View ACC's comprehensive library of clinical guidance.

Top 10 News Articles

1. New JACC Global Burden of CVD Report Shows Wide Variation Among Countries
2. DAPA-HF and DELIVER: Does Dapagliflozin Reduce Risk For Patients With Severe HF?
3. FLUNITY-HD: High-Dose Flu Vaccine Outperforms Standard Dose in Reducing Hospitalizations
4. RIVAWAR: Rivaroxaban as Effective as Warfarin For Post MI LV Thrombus
5. FRESH-UP: No Benefit in Limiting Fluid Intake in Patients With HF
6. DIGIT-HF: Digitoxin in Patients With HFrEF
7. Beta-Blocker Therapy Following MI the Focus of Late-Breaking Research at ESC Congress 2025
8. Research Suggests Long-Term Melatonin Use For Insomnia Increases HF Risk
9. VESALIUS-CV: Evolocumab vs. Placebo in Patients Without Previous MI or Stroke
10. Dive Into the 2026 Medicare Physician Fee Schedule Final Rule

Top 10 Cardiology Magazine Articles

1. Cover Story | Pulmonary Embolism: A Clinical Approach
2. Cover Story | Hidden in Plain Sight: SCAD as a Major Cause of MI in Women
3. Cover Story | Transformative Trends in CV Medicine For 2025
4. Cover Story | Picture Perfect: ACC.25
5. Feature | The Overlooked Cardiac Implications of Alpha-Gal Syndrome
6. Focus on HF | HFpEF: Where We Stand in 2025
7. From the Starting Line | Creating a Multidisciplinary Amyloidosis Program: A Practical Guide
8. Prioritizing Health | Dietary Approaches For Elevated LDL-C
9. Prioritizing Health | Sleep and CV Health
10. Prioritizing Health | Journey of the Health and Well-Being Coaching Profession

Top 10 Expert Analyses Articles

1. The Extravascular Implantable Cardioverter-Defibrillator: A Promising Novel Device
2. ULTIMATE-DAPT: Ticagrelor Alone vs. Ticagrelor Plus Aspirin From Month 1 to Month 12 Post PCI in Patients With ACS
3. Beyond Glycemic Control: Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist to Reduce the Burden of Peripheral Artery Disease
4. Updates in CV Disease Risk Assessment: An International Perspective
5. The Relationship Between Exercise and Longevity: Challenging the U-Shaped Hypothesis
6. Contrast Media in Advanced CV Imaging: Clinical Questions and Shifting Paradigms
7. The Evolving Role of Colchicine in Coronary Atherosclerosis Management: Timing May Be Everything
8. Describing the Sex-Specific Distribution of CAC Scores in South Asian Adults in the US
9. Multimodality Imaging in Pericardial Diseases and the Role of Imaging-Guided Therapies
10. Statins in Patients on Dialysis: A Mortality Benefit?

Top 10 Patient Case Quizzes

1. Tachycardia in Pregnancy
2. From Collapse to Clarity: Diagnosing a Teenager's Unexplained Syncope
3. The Management of Symptomatic Paroxysmal Atrial Fibrillation in a Tactical Athlete
4. Management of HFpEF
5. Baroreceptor Activation Therapy in HF
6. Sports Bound or Time to Ground? Sports Clearance in a Teenager With Bicuspid Aortic Valve
7. Game Time Diagnosis: Navigating Hypertrophy in a Young Athlete
8. A Stimulating Pediatric Electrocardiogram
9. Convulsion Confusion in a Child
10. Recurrent Myocarditis in a Child: More Than Meets the MRI

Top 10 Podcast Episodes

1. Eagle's Eye View: Colchicine vs. Placebo in Reducing CV Events: DOACs vs. Warfarin After TAVR; CSP vs. BiVP and Echo Response
2. Eagle's Eye View: Key Takeaways From ACC.25 Major Trials and Presentations
3. ACCEL Lite: Top Takeaways From the 2025 ACC/AHA Acute Coronary Syndrome Guideline
4. ACCEL Lite: A Look at the 2024 AHA/ACC Perioperative Guideline 
5. ACC CardiaCast: Conversations With Critical Care Cardiologists: Advanced Education and Training
6. ACC CardiaCast: Highlights From EuroPCR 2025
7. ACC CardiaCast: Decision Makers: Crafting Personalized AFib Care With a Team Approach
8. ACC Practice Made Perfect: Current Women Cardiologists in My Region and the Future
9. ACC Practice Made Perfect: Reducing Burnout Through AI Integration
10. ACC Practice Made Perfect: Overcoming Challenges of AI Implementation

2025 Contributors

Thank you to all the ACC.org 2025 contributors. See the list here.

Clinical Topics: Acute Coronary Syndromes, Anticoagulation Management, Arrhythmias and Clinical EP, Atherosclerotic Disease (CAD/PAD), Cardiac Surgery, Cardio-Oncology, Cardiovascular Care Team, Congenital Heart Disease and Pediatric Cardiology, COVID-19 Hub, Dyslipidemia, Geriatric Cardiology, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Pericardial Disease, Prevention, Pulmonary Hypertension and Venous Thromboembolism, Sports and Exercise Cardiology, Stable Ischemic Heart Disease, Valvular Heart Disease, Vascular Medicine, Diabetes and Cardiometabolic Disease