JACC in a Flash | Consistent Renal Benefit With Semaglutide in T2D/CKD; Late Pericardial Effusion Post LAAO

Featured topics and Editors' Picks from all of ACC's JACC Journals.

Journal of the American College of Cardiology
Semaglutide Delivers Consistent Kidney Benefit in T2D/CKD Across CVD Status

Semaglutide improved kidney and survival outcomes in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD), including those with established ASCVD, heart failure (HF) and high total CVD risk, according to a subgroup analysis of the FLOW trial published in an obesity-focused issue of JACC.

JACC: Advances
Late Pericardial Effusions After LAAO Implantation

Late pericardial effusion (LPE) post left atrial appendage occlusion (LAAO) was associated with negative patient outcomes, including mortality, suggesting the need for long-term surveillance, according to an analysis of the Manufacturer and User Facility Device Experience (MAUDE) Registry published in JACC: Advances.

JACC: Cardiovascular Imaging
Deferring Further Testing Rising in Low-Risk Chest Pain

In the evaluation of patients with low-risk chest pain, a rise in deferring additional testing has been observed, with lower rates of functional testing and invasive coronary angiography (ICA), and significant variation at the site level in the proportion of patients who underwent further noninvasive testing, according to a study published in JACC: Cardiovascular Imaging.

JACC: Cardiovascular Imaging
Micro- and Nanoplastics and Structural Plaque Vulnerability

Circulating levels of micro- and nanoplastics (MNPs) were associated with structural plaque vulnerability in acute coronary syndrome (ACS), based on optical coherence tomography (OCT), according to research published in JACC: Cardiovascular Imaging.

Resources

Clinical Topics: Acute Coronary Syndromes, Cardiovascular Care Team, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Pericardial Disease, Acute Heart Failure, Interventions and ACS, Interventions and Imaging, Angiography, Nuclear Imaging

Keywords: Cardiology Magazine, ACC Publications, CM-Jul-Aug-2026, Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic, Pericardial Effusion, Semaglutide, Heart Failure, Chest Pain, Registries, Chest Pain MI Registry, National Cardiovascular Data Registries, LAAO Registry, Computed Tomography, Troponin, Atrial Appendage, Polyvinyl Chloride, Gas Chromatography-Mass Spectrometry, Delivery of Health Care, Polyethylenes, Coronary Angiography, Acute Coronary Syndrome, Microplastics, Plaque, Atherosclerotic, Tomography, Optical Coherence