In this inaugural episode of the new podcast series produced by ACC’s Interventional Member Section, Dr. Poonam Velagapudi is joined by featured guests Drs. Debabrata Dash and Thomas Cuisset to discuss the Highlights from EuroPCR 2025.

Key insights from the 4D-ACS trial are explored, followed by a discussion on its practical impact in clinical settings. Major findings from the FAITAVI trial and the influence on procedural decision-making are highlighted. A recent meta-analysis is also reviewed, with commentary on how collective evidence may shape real-world interventional strategies. Tune in for a dynamic exchange on cutting-edge trials and their implications for the cath lab.

Related References:

1. The FAITAVI Trial: Angiography Versus Physiology-guided PCI in Patients Undergoing TAVI – 12-month Follow-up Data (PCR Online). 2025. Available at: https://www.pcronline.com/News/PCR-Press-Releases/2025/EuroPCR-2025-The-FAITAVI-trial-angiography-versus-physiology-guided-PCI-in-patients-undergoing-TAVI-12-month-follow-up-data. Accessed 6/24/25.
2. Ribichini F, Pesarini G, Fabris T, et al. A randomised multicentre study of angiography- versus physiologyguided percutaneous coronary intervention in patients with coronary artery disease undergoing TAVI: design and rationale of the FAITAVI trial. EuroIntervention. 2024 Apr 15;20(8):e504-e510. doi: 10.4244/EIJ-D-23-00679.
3. Jang Y, Park SD, Lee JP, et al. One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial. EuroIntervention. 2025 May 21:EIJ-D-25-00331. doi: 10.4244/EIJ-D-25-00331.