A special issue of JACC: Cardiovascular Imaging, published March 6, focuses on randomized trials in cardiovascular imaging. A collection of original research, imaging perspectives and state-of-the-art papers highlight the role outcomes-based imaging evidence plays in understanding, diagnosing and treating cardiovascular disease. Jagat Narula, DM, MD, PhD, MACC; Leslee J. Shaw, PhD, FACC; and Pamela Douglas, MD, MACC, use the Editor's Page to highlight the community's advances in cardiovascular imaging, stating that "10 years ago, the idea of a special issue of JACC: Cardiovascular Imaging devoted to randomized controlled trials would not have been possible." They suggest six areas to prioritize next and underscore that "how we address these questions will define the next decade of cardiovascular imaging research." Read more on ACC.org.