JACC: Advances invites cutting-edge submissions for an upcoming focus issue dedicated to the science and practice of preventive cardiovascular health. As cardiovascular disease continues to drive global morbidity and mortality, the issue will spotlight the latest original research, reviews, and perspectives that transform how to identify, manage and ultimately prevent disease. Innovative research, research letters, systematic reviews and meta-analyses, state-of-the-art reviews, policy statements and expert perspectives are welcome. Submit by Aug. 1.