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History

A Short History of Interventional Cardiology

• 3000 BC – Egyptians perform bladder catheterizations using metal pipes.

• 1929 – First documented human cardiac catheterization is performed by Dr. Werner Forssmann in Eberswald, Germany.

• 1964 – Dr. Charles Dotter, working with Dr. Melvin Judkins, introduces transluminal angioplasty (using multiple catheters of increasing diameter to open blocked arteries) in the United States; not accepted here, Dr. Dotter’s innovation is embraced in Europe by Dr. Eberhart Zeitler who then teaches it to Dr. Andreas Gruentzig.

• 1974 – Dr. Gruentzig performs first peripheral human balloon angioplasty.

• 1977 – First human coronary balloon angioplasty is performed intraoperatively by Dr. Gruentzig, Dr. Richard Myler, and Dr. Elias Hanna in San Francisco.

• 1978 – First percutaneous coronary angioplasty (PTCA) cases are performed in the United States by Dr. Myler in San Francisco and Dr. Simon Stertzer in New York; Dr. Gruentzig conducts first demonstration course in Zurich, Switzerland, attended by 28 pioneering physicians; International Dilation Society is established.

• 1980 – Dr. Gruentzig conducts the last of five demonstration courses in Zurich with Dr. Mason Sones, Dr. Judkins and Dr. Dotter in attendance; he then moves to Atlanta where be becomes Director of Interventional Cardiology at Emory University; National Heart, Lung and Blood Institute begins support of the existing PTCA registry; first 1,000 angioplasties are performed worldwide; guiding catheters are introduced.

• 1982 – Over-the-wire coaxial balloon systems are introduced, brachial guiding catheters and steerable guide wires are developed

• 1985 – A year of loss in the history of interventional medicine: Drs. Dotter, Sones, Judkins, and Gruentzig all pass away within nine months of each other.

• 1986 – Coronary atherectomy devices are introduced.

• 1987 – First use of coronary stents in the United States in humans by Dr. Spencer King and Dr. John Douglas.

• 1987 – 1993 – A large number of new interventional devices are invented and perfected; some, like lasers, are less effective than hoped for; others are approved and used worldwide; these devices include rotational atherectomy devices (Rotablator), intravascular ultrasound (IVUS), and stents.

• 1994 – 1997 – Stents become commonplace and eliminate many complications; CMS increases stent payment.

• 1997 – Over one million angioplasties are performed worldwide, making angioplasty the most common medical intervention in the world.

• 1999 – American Board of Internal Medicine (ABIM) introduces interventional cardiology certification.

• 2001 – Almost two million angioplasties are performed worldwide, with an estimated increase of 8 percent annually.

• 2002 – The 25th anniversary of the first angioplasty performed in a conscious patient. Drug-eluting stents (DES) are introduced; Cook, Inc. is approved to sell Achieve and V-Flex Plus PTX drug-eluting stents in Europe.

• 2003 – FDA approves the Cypher DES manufactured by Johnson & Johnson/Cordis for sale in the United States; CMS starts DES payment.

• 2003 – 2004 – Use of bare-metal stents in the United States drops from 75 percent to 19 percent, while use of DES rises from 23 percent to 63 percent (ACC’s NCDR registry data).

• 2004 – 21 percent of ACC membership is performing interventional procedures; FDA approves Boston Scientific’s Taxus DES.

• 2005 – ACC, SCAI, VIVA, CRT and others join forces to create i2 Summit 2006: Innovation in Intervention to be held concurrently with ACC’s 2006 Annual Scientific Session; Medtronic receives approval to market Endeavor DES in Europe; Global DES market is $5.5 billion and sales are estimated to be growing at nearly 40 percent.

This timeline has been adapted from information supplied by the independent educational health site Angioplasty.Org, which provides historical and current content on the field of angioplasty.

Sources:

American College of Cardiology, ACC-NCDR® National Cardiovascular Data Registry, © 2005

“Angioplasty From Bench to Bedside to Bench”, Spencer B. King, III, MD, Circulation. 1996;93:1621-1629.) © 1996 American Heart Association, Inc.

“Angioplasty Timeline”, www.angioplasty.org, www.ptca.org © Copyright Venture Digital LLC 1996-2005

“Cook Wins Approval To Sell Second Paclitaxel-Eluting Stent In Europe”, http://www.cookgroup.com/news/090502.html Copyright © Cook Group Incorporated 2005.

“the Edge”, Cardiovascular Services Briefing 2003, Sg2

“Medtronic Wins Europe's Backing For Coated Stent” Thomas M. Burton, Wall Street Journal, p.B3, August 1, 2005.