General Statement of Disclosure:

CONSULTING FEES/HONORARIA: United Therapeutics(SIGNIFICANT), Keros(MODEST), Acceleron/Merck(SIGNIFICANT), Medtronic(NONE), Bayer Healthcare Pharmaceuticals(SIGNIFICANT), Aerami(SIGNIFICANT) OWNERSHIP/PARTNERSHIP/PRINCIPAL: Intellia- employee(SIGNIFICANT) RESEARCH/RESEARCH GRANTS: Aerovate(SIGNIFICANT) OTHER FINANCIAL BENEFIT: Janssen Pharmaceuticals, Inc (Actelion)(MODEST)

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