Journal Scans

Kim A. Eagle, MD, MACC
Editor-in-Chief, ACC.org

By year’s end, the journal scan feature of ACC.org will have seen more than 300,000 unique visits in 2015. As you would expect, the Top 10 most visited journal scans surround a few clinical themes: anticoagulation in atrial fibrillation, antiplatelet therapies in CAD, and advances in interventional/structural heart treatments. Each of these areas represent common clinical conditions where there are rapid advances in treatment and for whom appropriate assimilation of these new treatments into daily practice is a challenge. ACC.org continues to seek ways to rapidly and concisely share these advances with our members.

— Kim A. Eagle, MD, MACC

• Triple Therapy for Acute Myocardial Infarction and Atrial Fibrillation (Journal of the American College of Cardiology)
• Duration of Dual Antiplatelet Therapy After DES (Journal of the American College of Cardiology)
• Analysis of Digoxin-Associated Mortality (European Heart Journal)
• PCI vs. CABG for Multivessel CAD (New England Journal of Medicine)
• Safety of Left Atrial Appendage Lariat Device (JAMA Internal Medicine)
• Atrial Fibrillation and CHA₂DS₂-VASc Scores of 0 or 1 (Journal of the American College of Cardiology)
• Net Clinical Benefit for Anticoagulation, Aspirin, or No Therapy in Low-Risk AF (Journal of the American College of Cardiology)
• Best Treatment for In-Stent Restenosis (Lancet)
• Benefit of Anticoagulation Unlikely in Patients with Atrial Fibrillation and a CHA₂DS₂-VASc Score of 1 (Journal of the American College of Cardiology)
• Complete vs. Culprit Artery Revascularization in STEMI With Multivessel Disease (Heart)

Clinical Trials

Deepak L. Bhatt, MD, MPH, FACC
Senior Associate Editor, Clinical Trials and News, ACC.org

As a service to its members and the cardiovascular community, ACC.org has been covering the most important clinical trials. In 2015, several landmark studies were presented or published. We have compiled a list of the Top 10 trials for 2015 based upon the number of page views. There were close to 100,000 views, reflecting the great interest in trial results. The number one spot went to the PEGASUS-TIMI 54 trial, PROMISE came in second, and SPRINT came in third. Rounding out the Top Ten were TOTAL, RIVER-PCI, MATRIX (bivalirudin versus heparin arm), FIGHT, OPTIDUAL, ALBATROSS, and MATRIX (radial versus femoral arm). These trials represent a diverse array of topics, illustrating the broad interests of our readers.

— Deepak L. Bhatt, MD, MPH, FACC

Disclosure: I served on the Executive Committee of PEGASUS-TIMI 54 and the DSMB of TOTAL (though I did not compile the statistics!).

• PEGASUS-TIMI 54: Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin–Thrombolysis in Myocardial Infarction 54
• PROMISE: Prospective Multicenter Imaging Study for Evaluation of Chest Pain
• SPRINT: Systolic Blood Pressure Intervention Trial
• TOTAL: Trial of Routine Aspiration Thrombectomy With PCI vs. PCI Alone in Patients With STEMI
• RIVER-PCI: Ranolazine in Patients With Incomplete Revascularization After Percutaneous Coronary Intervention
• MATRIX: Bivalirudin vs. Heparin: Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX: Bivalirudin vs. Heparin
• FIGHT: Functional Impact of GLP-1 for Heart Failure Treatment
• OPTIDUAL: Optimal Dual Antiplatelet Therapy
• ALBATROSS: Aldosterone Lethal Effects Blockade in Acute Myocardial Infarction Treated With or Without Reperfusion in Improve Outcome and Survival at Six Months Follow-Up
• MATRIX: Radial vs. Femoral: Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX: Radial vs. Femoral

Keywords: Acute Coronary Syndrome, Anticoagulants, Arrhythmias, Cardiac, Cardiac Surgical Procedures, Metabolic Syndrome, Angina, Stable, Heart Defects, Congenital, Dyslipidemias, Geriatrics, Heart Failure, Angiography, Diagnostic Imaging, Pericarditis, Secondary Prevention, Hypertension, Pulmonary, Sleep Apnea Syndromes, Sports, Aneurysm

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