Berlin Stent Study in Acute Myocardial Infarction - BESSAMI
IVUS-controlled heparinized stent vs. IVUS-guided PTCA in acute MI.
To compare IVUS-controlled heparinized stent implantation with IVUS-guided optimal balloon PTCA in the setting of acute MI.
Patients Screened: Not given
Patients Enrolled: 42 (ongoing)
Diagnosis of acute myocardial infarction, confirmed by angiography
Minimum vessel dimension of the smallest reference segment of at least 2.5mm.
IVUS-guided stent implantation vs IVUS-guided optimal PTCA.
The treatment groups for the study are established after successful PTCA. If no dissection is diagnosed by IVUS and angiography, and the IVUS-indicated TIMI flow is 3, patients are assigned to the control group. Optimal results without stenting are assumed to be obtained, and no further intervention is undertaken. If a dissection is diagnosed by IVUS or angiography, or if the TIMI flow is less than 3, patients are randomized into the stent group or the non-stent group.
During the first 3 1/2 months of the study, 42 patients have been enrolled.
No major events occurred in these patients during the acute intervention phase.
In 16% of the patients, IVUS detected a dissection that was missed by angiography.
Based on the preliminary results of the study, IVUS-guided primary stenting appears to be safe. IVUS may provide more accurate measurements of vessel size than QCA, which may underestimate vessel size.
Presented at the XXth Congress of the European Society of Cardiology, Vienna, 1998
Clinical Topics: Invasive Cardiovascular Angiography and Intervention
Keywords: Myocardial Infarction, Angioplasty, Balloon, Coronary, Stents
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