Coronary Angioplasty and Rotational Atherectomy Trial - CARAT
Aggressive vs conservative rotablator strategies in native coronary arteries.
To compare the early and late clinical and angiographic outcomes after conservative vs. aggressive atherectomy.
Patients Screened: Not given
Patients Enrolled: 222
Mean Follow Up: 6 months
Native coronary lesions
Vessel size 2.0-3.5 mm
Final diameter stenosis at end of procedure
Angiographic complications (side branch occlusion, no-reflow, severe dissection).
Target lesion revascularization at 6 months.
Conservative (burr:artery ratio < 0.7) versus aggressive (burr:artery ratio ≥ 0.7) rotational atherectomy strategies
A total of 104 patients (118 lesions) were randomized to the aggressive arm, and 118 patients (136 lesions) to the conservative arm.
Angiographic complication rates were 16.4% for patients in the aggressive arm compared to 8.2% in the conservative arm (p < 0.05).
Target lesion revascularization rates were 21% in the aggressive arm compared to 21.7% in the conservative arm.
A routine strategy using small burrs achieves similar immediate lumen enlargement and late target lesion revascularization compared to large burrs, but with fewer angiographic complications.
1. J Am Coll Cardiol 1998;31(Abstr Suppl):378A. Preliminary results
Keywords: Coronary Artery Disease, Atherectomy, Coronary
< Back to Listings