European Cooperative Acute Stroke Study III - ECASS III

Description:

Current guidelines recommend thrombolysis for acute ischemic stroke if the presentation is within 3 hours of symptom onset, given a large body of evidence from clinical trials showing a significant benefit. Subsequent studies also indicated that this benefit was not noted if 3-6 hours had elapsed since symptom onset. Data from observational studies, however, indicated that the window for benefit may extend up to 4.5 hours. The ECASS III trial is the first randomized trial to evaluate whether the...