Omapatrilat Reduces Pulse Pressure and Proximal Aortic Stiffness in Patients with Systolic Hypertension. Results of the Conduit Hemodynamics of Omipatrilat International Research Study. - Omapatrilat Reduces Pulse Pressure and Proximal Aortic Stiffness in Patients with Systolic Hypertension. Results of the Conduit Hemodynamics of Omipatrilat International Research Study.

Description:

Increased pulse pressure is an indicator of vascular stiffness and a major correlate of CV events in hypertension. The goal of this study was to determine if the administration of omapatrilat, a vasopeptidase with both ACE and neutral endopeptidase inhibitor activity, is associated with changes in vascular stiffness among patients with hypertension.