Reload With Clopidogrel Before Coronary Angioplasty in Subjects Treated Long Term With Dual Antiplatelet Therapy - RELOAD

Description:

Current evidence seems to indicate that due to individual variability in response to clopidogrel, as many as 30% of patients on maintenance clopidogrel (75 mg/day) may show elevated platelet reactivity. Earlier studies also seem to indicate that reloading patients already on maintenance therapy with 600 mg of clopidogrel is associated with improved platelet inhibition. Accordingly, the RELOAD study sought to determine whether a dose-response relationship could be demonstrated across three loadin...