TReprostinil Sodium Inhalation Used in the Management of Pulmonary Arterial Hypertension - TRIUMPH

Description:

The three main classes of medications used in pulmonary arterial hypertension (PAH) include prostacyclins (e.g., treprostinil, iloprost), endothelin receptor antagonists (e.g., bosentan), and phosphodiesterase (PDE) inhibitors (e.g., sildenafil). Although numerous trials have demonstrated the utility of the different agents as monotherapy in the treatment of PAH, very little data exist on the use of combination therapy. The current trial sought to study the safety and efficacy of inhaled trepros...