Randomized Olmesartan and Diabetes Microalbuminuria Prevention - ROADMAP


In patients with type 2 diabetes mellitus and hypertension, but normoalbuminuria and normal renal function, studies have demonstrated that early treatment with angiotensin-converting enzyme (ACE) inhibitors delays the onset of microalbuminuria. It is unclear if this is true for angiotensin-receptor blockers (ARBs) as well.

Accordingly, the ROADMAP trial sought to evaluate the safety and efficacy of olmesartan compared with placebo in delaying the development of microalbuminuria in pa...