Timing of Intervention in Patients With Acute Coronary Syndromes - TIMACS


Although patients with non–ST-elevation acute coronary syndromes (NSTE-ACS) have been shown to benefit with an early invasive therapy as compared with medical management, especially in high-risk patients, the optimal timing of an invasive strategy is still unknown. The TIMACS trial sought to study the efficacy of an early invasive strategy (within 24 hours of presentation) compared with a delayed invasive strategy (any time >36 hours following presentation).