Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction - WARCEF

Description:

Chronic systolic heart failure (CHF) is associated with a hypercoagulable state. Earlier trials on the use of warfarin in patients with CHF had included patients with atrial fibrillation (AF) and valvular heart disease, and thus, the true value of anticoagulation in patients with CHF but no other obvious cause for anticoagulation is unknown. Accordingly, the WARCEF trial sought to compare outcomes between the use of warfarin and aspirin in patients with CHF and normal sinus rhythm (NSR).<...