Integrated Biomarker and Imaging Study-2 - IBIS-2

Description:

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is found in necrotic lipid cores and it may contribute to plaque instability. The goal of the trial was to evaluate treatment with the Lp-PLA2 inhibitor darapladib compared with placebo in patients with angiographically documented coronary artery disease.