Optical coherence tomography for DES SAfety - ODESSA


Animal and autopsy studies of drug-eluting stents (DES) have demonstrated delayed healing and incomplete endothelialization at sites of DES overlap. It is unknown if the use of overlapping DES is associated with a higher incidence of incomplete or delayed stent coverage in humans. The ODESSA trial was designed to assess the utility of optical coherence tomography (OCT) in evaluating strut coverage and malapposition of different DES compared with bare-metal stents at a micron level in vivo.