Randomized Clinical Trial of Prehospital Induction of Mild Hypothermia in Out-of-Hospital Cardiac Arrest Patients Using a Rapid Infusion of 4°C Normal Saline - Prehospital Hypothermia for OHCA


Hospital cooling (32-34°C) improves neurologic outcome after out-of-hospital cardiac arrest (OHCA), especially ventricular fibrillation (VF). It is unknown if institution of more rapid cooling (i.e., prehospital cooling) would have better outcomes compared to hospital alone cooling.

The current trial sought to determine whether prehospital cooling improves outcomes from cardiac arrest with VF or non-VF compared with hospital-only cooling.