Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure - TIME-CHF


While earlier studies have suggested that B-type natriuretic peptide (BNP)-guided therapy may have a beneficial role in the management of chronic heart failure, there are very little data on this topic in elderly patients. Accordingly, the goal of this trial was to investigate the efficacy of intensive BNP-guided therapy compared with standard symptom-guided therapy in patients with heart failure, with the specific inclusion of patients ≥75 years of age.