RELAXin in Acute Heart Failure - RELAX-AHF


Relaxin is a peptide hormone secreted during pregnancy that is associated with significant hemodynamic changes including increasing cardiac output and decreasing systemic vascular resistance. A similar pharmacological profile might have beneficial effects in patients with acute decompensated heart failure (ADHF). Serelaxin is a recombinant version of human relaxin-2. The current trial sought to compare the safety and efficacy of serelaxin in patients presenting with ADHF.