Intracoronary Stenting and Antithrombotic Regimen: Safety and Efficacy of 6 Months Dual Antiplatelet Therapy After Drug-Eluting Stenting - ISAR-SAFE


Current guidelines recommend that dual antiplatelet therapy (DAPT) with aspirin and an ADP receptor inhibitor be continued for a minimum of 12 months following drug-eluting stent (DES) percutaneous coronary intervention (PCI). The optimal duration, however, remains unclear. This trial sought to investigate if 6 months of DAPT was superior to 12 months in patients undergoing DES PCI.

Contribution to the Literature: The ISAR-SAFE trial showed that 6 months of DAPT may be noninferior to 1...