Randomized, Controlled Trial of Individualized Heparin and Protamine Management in Infants Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Study Questions:

Are postoperative clinical outcomes improved in children less than 1 year of age undergoing cardiopulmonary bypass (CPB) with the use of individualized heparin management with Hemostasis Management System (HMS) Plus rather than traditional weight-based anticoagulation management using activated clotting time (ACT)?