Timeliness of Tissue-Type Plasminogen Activator Therapy in Acute Ischemic Stroke: Patient Characteristics, Hospital Factors, and Outcomes Associated With Door-to-Needle Times Within 60 Minutes

Study Questions:

What were the presenting characteristics of acute ischemic stroke patients treated with intravenous tissue-type plasminogen activator (tPA) within 3 hours of symptom onset in whom a door-to-needle time ≤60 minutes was achieved, hospital-level variation in door-to-needle times, in-hospital clinical outcomes, and temporal trends in timely thrombolytic care?