Results:

A total of 5,011 patients were included in the three studies: 4,885 subjects (1,164 women, 3,721 men) completed 2 years of follow-up. Women were older than the men and were more likely to have diabetes, obesity, and hypertension, but less likely to be smokers, or have a prior history of MI or prior surgical revascularization. Women were also more likely to have a smaller reference diameter of the target vessel and a lower SYNTAX score. After adjustment for baseline differences, women and men had a similar risk of cardiac death or MI (odds ratio [OR], 1.13; 95% CI, 0.82-1.56; p = 0.44), cardiac death (OR, 1.04; 95% CI, 0.61-1.80; p = 0.87), and MI (OR, 1.07; 95% CI, 0.75-1.53; p = 0.71) at 2 years. Similarly, risks of target lesion revascularization (OR, 1.09; 95% CI, 0.77-1.54; p = 0.62), target vessel revascularization (OR, 0.88; 95% CI, 0.63-1.22; p = 0.43), and definite or probable stent thrombosis (OR, 0.73; 95% CI, 0.38-1.38; p = 0.33) were comparable for women and men. Follow-up angiography showed no differences in terms of in-stent late loss and in-segment binary restenosis (8.5% vs. 8.5%, p = 0.76).